In this circumstance, when I start VirtualBox (assuming VB manager was not started before renaming) you will see the mark “Inaccessible” next to the name of the virtual machine and, if selected, the information about this error as shown below. Change the path to the location with the virtual machine files due to the drive letter being changed, the folder containing the virtual machine files has been renamed, user folder (if the virtual machine folders were inside, as is usually the default).There are multiple reasons for E_FAIL 0x80004005 error in VirtualBox, let's start with some of the simplest ones that are very easy to fix: Fix error code E_FAIL 0x80004005 in VirtualBox Some of the readers may find the VirtualBox Virtual Machines for Beginners post helpful. This tutorial details the most common causes of error 0x80004005 in VirtualBox virtual machines and the alternatives to fix the problem. Many users encounter MachineWrap error E_FAIL 0x80004005, MediumWrap and other components when starting and, in some cases, before starting a virtual machine in VirtualBox, regardless of the operating system installed on it (Windows 10 and earlier, Linux and others).

Vbox 0x80004005